Physiological, Biochemical and Modern Biotechnological Approach to Improvement of Rauwolfia serpentina

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Physiological, Biochemical and Modern Biotechnological Approach to Improvement of Rauwolfia serpentina

Rauwolfia serpentina also known as Sarpagandha (Apocynaceae) is an integral part of Ayurvedic medical system in India for over centuries for the treatment of various ailments. The leaves and roots ofRauwolfiaserpentina contain alkaloids which are secondary metabolites. Major alkaloids identified are Reserpine, Rauwolfine, Serpentine, Sarpagine, Ajmaline, Yohimbine and Ajmalicine.The present pap...

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Rauwolfia Serpentina in Essential Hypertension

jHauwolfia serpentina has been known as a medicinal plant in India for a long time but its use in the treatment of hypertension is of comparatively recent origin. The dried root contains 1 per cent of total alkaloids besides resin, starch, potassium carbonate, phosphate, silicate and traces of iron and manganese (Sen and Bose, 1931). Siddiqui and Siddiqui (1931) found two groups of alkaloids an...

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Rauwolfia serpentina (serpasil) in psychiatry.

The therapeutic problem of satisfactorily controlling acute and chronic states of psychomotor excitement is an ever-present one confronting psychiatrists engaged in hospital practice. Admittedly, the application of current methods of treatment, such as systematic pharmacological sedation by means of barbiturates and other drugs or electroconvulsive therapy, will in most cases control excited be...

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Pharmacognostical Profiling on the Root of Rauwolfia Serpentina

Each medicinal plant and the specific plant part used as crude drug material contain active or major chemical constituents with a characteristic profile that can be used for chemical quality control and quality assurance. So the increasing demand for herbal medicines has inevitably led to maintaining the quality and purity of herbal raw materials and finished products. WHO acknowledged that Pha...

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Rauwolfia serpentina in the treatment of angina pectoris.

Fifteen subjects with coronary artery disease and angina pectoris were given alternate courses of the alseroxylon fraction of Ratiwolfia serpentina and placebo. Fourteen improved on the drug as determined by independent clinical evaluations and the "Daily Report Card" data. Seven developed normal electrocardiograms, 2-step tests or ballistocardiograms, that previously had been abnormal. Alserox...

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ژورنال

عنوان ژورنال: IOSR Journal of Pharmacy and Biological Sciences

سال: 2013

ISSN: 2319-7676,2278-3008

DOI: 10.9790/3008-0627378